Binding of neomycin and analogues by fatty acids in vitro.

Binding of neomycin and analogues by fatty acids in vitro

The activity of antibiotics in vivo may be reduced by their interaction with constituents of blood or tissues, for example, the protein binding of penicillin and the binding of neomycin to mucus (Saggers and Lawson, 1966). During a study of the action of antibiotics on cutaneous bacteria in vitro, neomycin was found to precipitate long-chain fatty acids of the type present in skin. As neomycin ...

Effects of feed restriction and dietary fat type on mRNA expression of liver fatty acid-binding protein (L-FABP) in broilers

Background: Liver fatty acid-binding protein (L-FABP) is the main cytosolic binding site for long chain fatty acids in hepatocytes. FABPs enhance the uptake of fatty acids into the cell by increasing their concentration due to decreasing concentration of unbound fatty acids inside the cell. Objectives: The aim of this study was to evaluate the effects of dietary unsaturated to saturated fatty a...

Improvement of Semen Quality in Holstein Bulls during Heat Stress by Dietary Supplementation of Omega-3 Fatty Acids

پاسخ متفاوت سلولهای قلبی به اسیدهای چرب اشباع و غیر اشباع

Introduction & Objective: The link between dietary fat and coronary heart disease has attracted much attention since the effect of long?chain fatty acids (LCFA) on gene transcription has been established, which in part, these effects can be explained by the regulation of gene transcription. In this study, the P19CL6 cardiac cell?line was targeted for the investigation of (i) the effects of long...

P-14: In Vitro Comparison of Different Dietary Omega-3/Omega-6 Fatty Acid Ratios and Vitamin E on The Rat Semen Quality

Background: Beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on the male fertility are widely described in the literature. However, there is little information about the effect of dietary n-3/n-6 ratios and Vit E on the male reproduction. The aim of this study was to evaluate the influence of dietary PUFAs on the rat sperm characteristics after eight weeks oil consumption. Mate...